(S,R,S)-AHPC-C6-NH2 (hydrochloride)

(S,R,S)-AHPC-C6-NH2 (hydrochloride)

• CAS Number: 2360522-76-3
• UNSPSC Description: (S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-c5-nh2-hydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: [H]Cl.O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCN)=O
• Molecular Weight: 594.21
• References & Citations: [1]Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported