(S,S,R)-AHPC-C6-NH2 (hydrochloride)

• UNSPSC Description:

  (S,S,R)-AHPC-C6-NH2 hydrochloride is the hydrochloride salt form of (S,S,R)-AHPC-C6-NH2 (HY-143276). (S,S,R)-AHPC-C6-NH2 hydrochloride is the E3 ligase ligand-linker conjugate, which can be utilized for synthesis of PROTAC HL-8 (HY-143275)[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/s-s-r-ahpc-c6-nh2-hydrochloride.html

• Smiles:

  NCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C[C@@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O.[H]Cl

• Molecular Weight:

  594.21

• References & Citations:

  [1]Wang H, et al. Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase. Bioorg Med Chem. 2022 May 1;61:116707.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported