(S,R,S)-AHPC-C3-NH2 (hydrochloride)

(S,R,S)-AHPC-C3-NH2 (hydrochloride)

• Product Name Alternative: VH032-C3-NH2 (hydrochloride)
• CAS Number: 2940858-65-9
• UNSPSC Description: (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in?PROTAC?technology[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-c3-nh2-hydrochloride.html
• Purity: 96.38
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: NCCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)=O.[H]Cl
• Molecular Weight: 552.13
• References & Citations: [1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, stored under nitrogen)
• Clinical Information: No Development Reported