OMDM-5

• Description :

  OMDM-5 is a selective inhibitor of anandamide cellular uptake (ACU), with a Ki of 4.8 μM. OMDM-5 is also a potent vanilloid receptor type 1 (VR1, TRPV1) agonist, with an EC50 of 75 nM, and shows weakly active as cannabinoid receptor type 1 (CB1) ligand (Ki=4.9 μM) [1].

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite; TRP Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/omdm-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCCCCC/C=C\CCCCCCCC(NNCC1=CC=C(O)C(OC)=C1)=O

• Molecular Formula :

  C26H44N2O3

• Molecular Weight :

  432.64

• References & Citations :

  [1]Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65 (9) :1473-81.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [616884-66-3]