OMDM-6

• Description :

  OMDM-6 is a hybrid agonist of vanilloid receptor type 1 (VR1, TRPV1) (EC50=75 nM) and cannabinoid receptor type 1 (CB1) (Ki=3.2 μM) . OMDM-6 inhibits anandamide cellular uptake (ACU) with a Ki of 7.0 μM[1].

• CAS Number :

  [616884-67-4]

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor; Endogenous Metabolite; TRP Channel

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/omdm-6.html

• Concentration :

  10mM

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NNCC1=CC=C(O)C(OC)=C1)=O

• Molecular Formula :

  C28H42N2O3

• Molecular Weight :

  454.64

• References & Citations :

  [1]Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65 (9) :1473-81.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported