8-NH2-ATP

8-NH2-ATP

• CAS Number: 35874-49-8
• UNSPSC Description: 8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase[1][2].
• Target Antigen: DNA/RNA Synthesis; Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/8-nh2-atp.html
• Solubility: 10 mM in DMSO
• Smiles: NC(N([C@]([C@@H]([C@@H]1O)O)([H])O[C@@H]1CO[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)C2=NC=N3)=NC2=C3N
• Molecular Weight: 522.20
• References & Citations: [1]Nancy L Krett, et al. 8-amino-adenosine is a potential therapeutic agent for multiple myeloma. Mol Cancer Ther. 2004 Nov;3(11):1411-20.|[2]Yuji Matsuzaki, et al. ATP-association to intrabacterial nanotransportation system in Vibrio cholera. Med Mol Morphol. 2015 Dec;48(4):225-34.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported