Dehydro Olmesartan

Dehydro Olmesartan

• CAS Number: 172875-98-8
• UNSPSC Description: Dehydro Olmesartan is a derivative of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study[1][2].
• Target Antigen: Angiotensin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/dehydro-olmesartan.html
• Purity: 99.43
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=C(C(C)=C)N=C(CCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2)O
• Molecular Weight: 428.49
• References & Citations: [1]Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7.|[2]Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported