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Bis-SS-C3-NHS ester

CAT: 0804-HY-133584-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133584-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
CAS Number
98604-88-7
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-ss-c3-nhs-ester.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)CCCSSCCCC(ON2C(CCC2=O)=O)=O
Molecular Formula
C16H20N2O8S2
Molecular Weight
432.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker

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