MTL-CEBPA

• Description:

  MTL-CEPBA is a small activating RNA targeting for upregulation of C/EBPα. MTL-CEPBA has anti-inflammatory and anti-cancer activity[1].

• Product Name Alternative:

  CEBPA-51

• UNSPSC:

  12352208

• Target:

  MicroRNA

• Type:

  Oligonucleotides

• Related Pathways:

  Epigenetics

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/mtl-cebpa.html

• Purity:

  95.52

• Solubility:

  10 mM in H2O

• Smiles:

  [MTL-CEBPA]

• Molecular Weight:

  13464.27

• References & Citations:

  [1]Jiehua Zhou, et al. Anti-inflammatory Activity of MTL-CEBPA, a Small Activating RNA Drug, in LPS-Stimulated Monocytes and Humanized Mice. Mol Ther. 2019 May 8;27 (5) :999-1016.|[2]Reebye V, Huang KW, Lin V, et al. Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene. 2018;37 (24) :3216-3228. |[3]Combination therapies comprising C/EBPα-targeted short-activating RNA (saRNA) . WO2022229644A1

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  Phase 2

• CAS Number:

  2862057-05-2