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5-Aminouridine

CAT: 0804-HY-130802-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130802-01Size:1 mg
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Description
5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2].
CAS Number
2149-76-0
UNSPSC
12352005
Target
Fungal; Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/5-aminouridine.html
Purity
99.31
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C(N2)=O)C=C(N)C2=O)O1
Molecular Formula
C9H13N3O6
Molecular Weight
259.22
References & Citations
[1]Smith DA, et al. Studies on 5-aminouridine. Biochim Biophys Acta. 1966 May 19;119 (2) :221-8.|[2]ROBERTS M, et al. Antimetabolite activity of uridine and cytidine derivatives. J Biol Chem. 1952 Feb;194 (2) :695-701. PMID: 14927662.. . .|[3]MR, et al. Detection of attomole quantities [correction of quantitites] of DNA targets on gold microelectrodes by electrocatalytic nucleobase oxidation. Anal Chem. 2003 Dec 1;75 (23) :6586-92.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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