(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc

• CAS Number: 2409007-40-3
• UNSPSC Description: (S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is a synthesized E3 ligase ligand-linker conjugate which is used for the EED-targeted PROTAC[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-o-ph-peg1-nh-boc.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C)([C@H](NC(COC1=CC=C(OCCNC(OC(C)(C)C)=O)C=C1)=O)C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C=C3)C4=C(N=CS4)C)=O)=O)C
• Molecular Weight: 723.88
• References & Citations: [1]Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported