11β-Prostaglandin E2

• UNSPSC Description:

  11β-Prostaglandin E2 (11β-Dinoprostone), a Prostanoid derivative, inhibits [3H]PGE2 binding to hypothalamic membranes in the rat with a Ki of 53.3 nM[1].

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/11β-prostaglandin-e2.html

• Purity:

  99.0

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@@H]1O)=O)C/C=C\CCCC(O)=O

• Molecular Weight:

  352.47

• References & Citations:

  [1]F Dray, M Heaulme, et al. Prostaglandins of the E series inhibit release of noradrenaline in rat hypothalamus by a mechanism unrelated to classical alpha 2 adrenergic presynaptic inhibition. Neuropharmacology. 1984 Apr;23(4):457-62.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Solution, -20°C, 2 years

• Clinical Information:

  No Development Reported

• CAS Number:

  38310-90-6