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CDK9-IN-9

CAT: 0804-HY-130001Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-130001Size:1 Each
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Description
CDK9-IN-9 (example 2) is a potent and selective CDK9 inhibitor with an IC50 of 1.8 nM. CDK9-IN-9 inhibits CDK2 with an IC50 of 155 nM. CDK9-IN-9 has anti-cancer activity[1].
CAS Number
[2246956-84-1]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk9-in-9.html
Solubility
10 mM in DMSO
Smiles
CS(CC1=CC2=CC(NC3=NC=C(C(C4=CC=C(C(NCCCCO2)=C4)F)=N3)F)=C1)(=O)=N
Molecular Formula
C22H23F2N5O2S
Molecular Weight
459.51
References & Citations
[1]Ulrich LÜCKING, et al. Novel ptefb inhibiting macrocyclic compounds. WO2018177889A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2; CDK9

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