Products for Research Use Only

Dinoprost-d4

CAT: 0804-HY-12956SSize: 25 μg (278.93 μM x 250 μL in Methyl Acetate)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-12956SSize:25 μg (278.93 μM x 250 μL in Methyl Acetate)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dinoprost-d4 is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL) . Dinoprost plays a key role in the onset and progression of labour[1][2].
CAS Number
34210-11-2
Product Name Alternative
Prostaglandin F2a-d4; PGF2α-d4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Prostaglandin Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease; Others
Field of Research
Endocrinology
Concentration
278.93 μM * 250 μL in Methyl acetate
Purity
99.9
Solubility
10 mM in DMSO
Smiles
OC(CC([2H])([2H])C([2H])([2H])/C=C\C[C@@H]([C@H](C1)O)[C@H]([C@@H]1O)/C=C/[C@@H](O)CCCCC)=O
Molecular Formula
C20H30D4O5
Molecular Weight
358.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47 (3) :938-45.|[3]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
FP

Popular Products