Dinoprost

• Product Name Alternative:

  Prostaglandin F2α; PGF2α

• UNSPSC Description:

  Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour[1][2].

• Target Antigen:

  Apoptosis; Autophagy; Endogenous Metabolite; Prostaglandin Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Autophagy;GPCR/G Protein;Metabolic Enzyme/Protease

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/Dinoprost.html

• Purity:

  99.63

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

• Smiles:

  CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O

• Molecular Weight:

  354.48

• References & Citations:

  [1]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):938-45.|[2]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  551-11-1