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Dinoprost

CAT: 0804-HY-12956-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12956-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL) . Dinoprost plays a key role in the onset and progression of labour[1][2].
CAS Number
551-11-1
Product Name Alternative
Prostaglandin F2α; PGF2α
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Endogenous Metabolite; Prostaglandin Receptor
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/Dinoprost.html
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O
Molecular Formula
C20H34O5
Molecular Weight
354.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47 (3) :938-45.|[2]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
FP; Human Endogenous Metabolite
Citation 01
ACS Pharmacol Transl Sci. 2025 Oct 4.|Int J Mol Sci. 2023 Apr 10;24 (8) :7012.|Nat Commun. 2023 May 9;14 (1) :2668.|Phytomedicine. 2025 May 14:143:156866.|Patent. US20250154162A1.|Patent. US20250250283A1.

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