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Dinoprost-d9

CAT: 0804-HY-12956S1-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12956S1-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dinoprost-d9 is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL) . Dinoprost plays a key role in the onset and progression of labour[1][2].
Product Name Alternative
Prostaglandin F2a-d9; PGF2α-d9
UNSPSC
12352211
Target
Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Prostaglandin Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease; Others
Field of Research
Endocrinology
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)/C=C/[C@H](CC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])O)C/C=C\CCCC(O)=O
Molecular Formula
C20H25D9O5
Molecular Weight
363.54
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47 (3) :938-45.|[3]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
FP

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