Abemaciclib metabolite M20-d8

Abemaciclib metabolite M20-d8

• UNSPSC Description: Abemaciclib metabolite M20-d8 is the deuterium labeled Abemaciclib metabolite M20. Abemaciclib metabolite M20 (LSN3106726), the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor[1].
• Target Antigen: CDK
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Cancer
• Purity: 99.26
• Solubility: DMSO : 200 mg/mL (ultrasonic)
• Smiles: CC(C)N1C2=CC(C3=C(C=NC(NC4=NC=C(C=C4)CN(C([2H])(C5([2H])[2H])[2H])C([2H])(C([2H])(N5CC)[2H])[2H])=N3)F)=CC(F)=C2N=C1CO
• Molecular Weight: 530.64
• References & Citations: [1]Morschhauser F, et al. Clinical activity of abemaciclib in patients with relapsed or refractory mantle cell lymphoma - a phase II study. Haematologica. 2021;106(3):859-862. Published 2021 Mar 1.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported