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Cytochalasin H

CAT: 0804-HY-129325Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-129325Size:1 mg
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Description
Cytochalasin H is a nature product that could be isolated from fungus Phomopsis sp. Cytochalasin H inhibits cell growth and induces apoptosis. Cytochalasin H has anti-angiogenic activity. Cytochalasin H is an antibiotic and has antibacterial activity[1][2][3].
CAS Number
53760-19-3
UNSPSC
12352005
Hazard Statement
H300+H310+H330, H361
Target
Antibiotic; Apoptosis; Bacterial; Bcl-2 Family; Caspase
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/cytochalasin-h.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@]12[C@](/C=C/C[C@H](C)C[C@@](C)(O)/C=C/[C@H]2OC(C)=O)([H])[C@@H]3O)N[C@@H](CC4=CC=CC=C4)[C@]1([H])[C@H](C)C3=C
Molecular Formula
C30H39NO5
Molecular Weight
493.63
Precautions
H300+H310+H330, H361
References & Citations
[1]Ma Y, et, al. Cytochalasin H isolated from mangrove‑derived endophytic fungus induces apoptosis and inhibits migration in lung cancer cells. Oncol Rep. 2018 Jun;39 (6) :2899-2905.|[2]Yi JM, et, al. In Vivo Anti-tumor Effects of the Ethanol Extract of Gleditsia sinensis Thorns and Its Active Constituent, Cytochalasin H. Biol Pharm Bull. 2015;38 (6) :909-12.|[3]Jouda JB, et, al. Antibacterial and cytotoxic cytochalasins from the endophytic fungus Phomopsis sp. harbored in Garcinia kola (Heckel) nut. BMC Complement Altern Med. 2016 Nov 14;16 (1) :462.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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