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AZD5099

CAT: 0804-HY-12888Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-12888Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by Gram-positive and fastidious Gram-negative bacteria[1].
CAS Number
[907543-25-3]
UNSPSC
12352005
Hazard Statement
H302
Target
Bacterial; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/azd5099.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N=C(N(CC[C@H]1NC(C(NC(C)=C2Cl)=C2Cl)=O)C[C@@H]1OC)S3)=C3C(O)=O)N[C@@H](C)COC
Molecular Formula
C21H27Cl2N5O6S
Molecular Weight
548.44
Precautions
P264-P270-P330-P501
References & Citations
[1]Gregory S Basarab, et al. Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099) . J Med Chem. 2014 Jul 24;57 (14) :6060-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Topo II

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