JYL-273

• Description:

  JYL-273 is a TRPV1 agonist, with the IC50 of 361 nM in CHO-TRPV1 cell lines[1].

• UNSPSC:

  12352005

• Target:

  TRP Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/jyl-273.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)(C)C(OCC(CC1=CC=C(C(C)(C)C)C=C1)CC(NCC2=CC=C(O)C(OC)=C2)=S)=O

• Molecular Formula:

  C28H39NO4S

• Molecular Weight:

  485.68

• References & Citations:

  [1]Czikora Á, Lizanecz E, et al. Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1. Br J Pharmacol. 2012;165 (6) :1801-1812.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1391826-17-7]