HM03 (trihydrochloride)
CAT:
804-HY-125974A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HM03 (trihydrochloride)
- CAS Number: 1082532-95-3
- UNSPSC Description: HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity[1].
- Target Antigen: HSP
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hm03-trihydrochloride.html
- Solubility: 10 mM in DMSO
- Smiles: OC1=CC=C(NC2=C(C=C(OC)C=C3)C3=NC4=CC(Cl)=CC=C42)C=C1CN5CCN(C)CC5.[H]Cl.[H]Cl.[H]Cl
- Molecular Weight: 572.35
- References & Citations: [1]Huang M, et al. Structure-based design of HSPA5 inhibitors: from peptide to small molecule inhibitors. Bioorg Med Chem Lett. 2013;23(10):3044-3050.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported