Entacapone acid

• Description :

  Entacapone acid (Tyrphostin AG1290) is a tyrosine kinase inhibitor. Entacapone acid reduces hepatic protein synthesis rate (HPS) in vivo[1].

• Product Name Alternative :

  Tyrphostin AG1290

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  C-Met/HGFR

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/entacapone-acid.html

• Purity :

  98.86

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(/C(C#N)=C/C1=CC([N+]([O-])=O)=C(C(O)=C1)O)O

• Molecular Formula :

  C10H6N2O6

• Molecular Weight :

  250.16

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Nakagohri T, et al. The effects of prostaglandin E1 and tyrosine kinase inhibitors on energy status and protein synthetic ability in hepatic ischemia-reperfusion injury. Surg Today. 1998;28 (5) :517-21.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [160391-70-8]