Entacapone acid

• UNSPSC Description:

  Entacapone acid (Tyrphostin AG1290) is a tyrosine kinase inhibitor. Entacapone acid reduces hepatic protein synthesis rate (HPS) in vivo[1].

• Target Antigen:

  c-Met/HGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/entacapone-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(/C(C#N)=C/C1=CC([N+]([O-])=O)=C(C(O)=C1)O)O

• Molecular Weight:

  250.16

• References & Citations:

  [1]Nakagohri T, et al. The effects of prostaglandin E1 and tyrosine kinase inhibitors on energy status and protein synthetic ability in hepatic ischemia-reperfusion injury. Surg Today. 1998;28(5):517-21.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  160391-70-8