Products for Research Use Only
RegisterLogin

Azaphilone-9

CAT: 0804-HY-124844Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-124844Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction (IC50=1.2 μM) by binding RNA-binding protein Hu antigen R (HuR) . The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression[1].
CAS Number
1448460-87-4
Product Name Alternative
AZA-9
UNSPSC
12352005
Target
HuR
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azaphilone-9.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C)(OC(C)=O)C(C2=COC(/C=C/C(C)=C/[C@@H](C)CC)=CC2=C1Br)=O
Molecular Formula
C21H23BrO5
Molecular Weight
435.31
References & Citations
[1]Kaur K, et al. The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro. PLoS One. 2017 Apr 17;12 (4) :e0175471.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-116302-01MMP-9-IN-9
HY-N3453Isotaxiresinol 9,9'-acetonide
HY-179616AT-9
HY-168792-01(±) -9-Nor-9α-hydroxy Hexahydrocannabinol
HY-W510032-019-Ethoxy-9-oxononanoic acid
HY-168793-01(±) -9-Nor-9β-hydroxy Hexahydrocannabinol
HY-N10011,9-Caryolanediol 9-acetate
HY-N34759,9'-O-Isopropyllidene-isolariciresinol
HY-N91014,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan
HY-W019610S-019,9-Dimethylfluoren-2-amine-d6

Alternative Products

CatalogName
MBS5815170Azaphilone-9
OR1023755-019H,9'H-[9,9'-Bifluorene]-9,9'-Dicarbaldehyde
OR1074018-019,9,9',9',9'',9''-Hexahexyl-9H,9'H,9''H-2,2':7',2''-terfluorene
OR1032399-01[9,9'-Bi-9H-Fluorene]-9,9'-dimethanol
FD1472339,9-Dichlorofluorene
sc-4874199,9'-Bifluorenyl
OR1062050-019,9'-Bicarbazole
OR75921-019,9-Dihexylfluorene
sc-4918789,9'-Bianthracene
B10660-019,9'-Bifluorene

Popular Products