2-Trifluoromethyl-2'-methoxychalcone

• UNSPSC Description:

  2-Trifluoromethyl-2'-methoxychalcone is a chalcone derivative. 2-Trifluoromethyl-2'-methoxychalcone is a potent Nrf2 activator. 2-Trifluoromethyl-2'-methoxychalcone can be used for oxidative stress and inflammation related diseases research[1].

• Target Antigen:

  Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/2-trifluoromethyl-2-methoxychalcone.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2C(F)(F)F

• Molecular Weight:

  306.28

• References & Citations:

  [1]Kumar V, et al. Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells. J Med Chem. 2011 Jun 23;54(12):4147-59.

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  Store at room temperature 3 years

• Clinical Information:

  No Development Reported

• CAS Number:

  1309371-03-6