4'-Methoxychalcone

• Description:

  4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. 4'-Methoxychalcone modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PARP

• Type:

  Natural Products

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/4-methoxychalcone.html

• Purity:

  99.82

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C (C1=CC=C (OC) C=C1) /C=C/C2=CC=CC=C2

• Molecular Formula:

  C16H14O2

• Molecular Weight:

  238.29

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Han Y, et al. Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells. Food Chem Toxicol. 2017 Aug;106 (Pt A) :17-24.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  959-23-9