4'-Methoxychalcone

• Description :

  4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. 4'-Methoxychalcone modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PARP

• Type :

  Natural Products

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/4-methoxychalcone.html

• Purity :

  99.82

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC=C(OC)C=C1)/C=C/C2=CC=CC=C2

• Molecular Formula :

  C16H14O2

• Molecular Weight :

  238.29

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Han Y, et al. Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells. Food Chem Toxicol. 2017 Aug;106 (Pt A) :17-24.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [959-23-9]