SMPH Crosslinker

• Description:

  SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/smph-crosslinker.html

• Purity:

  95.0

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(CCCCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O

• Molecular Formula:

  C17H21N3O7

• Molecular Weight:

  379.36

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers

• CAS Number:

  [367927-39-7]