Arg-Gly-Asp-Ser (TFA)

Arg-Gly-Asp-Ser (TFA)

• UNSPSC Description: Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser (TFA) directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1[1].
• Target Antigen: Integrin
• Type: Peptides
• Related Pathways: Cytoskeleton
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/arg-gly-asp-ser-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](CO)C(O)=O)[C@H](CC(O)=O)NC(CNC([C@@H](N)CCCNC(N)=N)=O)=O.OC(C(F)(F)F)=O
• Molecular Weight: 547.44
• References & Citations: [1]Aguzzi MS, et al. Intracellular targets of RGDS peptide in melanoma cells. Mol Cancer. 2010 Apr 22;9:84.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported