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Scaff10-8

CAT: 0804-HY-121667Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121667Size:1 Each
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Description
Scaff10-8, bound to RhoA, inhibits the AKAP-Lbc-mediated RhoA activation[1].
CAS Number
777857-56-4
UNSPSC
12352005
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/scaff10-8.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC1=C(C2=CC3=C(C=C2OC1=O)OC=C3C4=CC=C(C=C4)OC)C)O
Molecular Formula
C22H18O6
Molecular Weight
378.37
References & Citations
[1]Schrade K, et al. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018;13 (1) :e0191423. Published 2018 Jan 26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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