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Methicillin (sodium hydrate)

CAT: 0804-HY-121544ASize: 1 EachDry Ice: NoHazardous: No
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Description
Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs) . Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis[1].
CAS Number
7246-14-2
UNSPSC
12352005
Target
Antibiotic; Bacterial; Histamine Receptor; Penicillin-binding protein (PBP)
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/methicillin-sodium-hydrate.html
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])[C@H](N1C2=O)C(C)(S[C@@]1([C@@H]2NC(C3=C(C=CC=C3OC)OC)=O)[H])C.O
Molecular Formula
C17H21N2NaO7S
Molecular Weight
420.41
References & Citations
[1]Sharon S. Castle. Methicillin. xPharm: The Comprehensive Pharmacology Reference 2007, Pages 1-4. |[2]Jaime Carrizosa, et al. Treatment of Experimental Staphylococcus aureus Endocarditis: Comparison of Cephalothin, Cefazolin, and Methicillin. Antimicrob Agents Chemother. 1978 Jan; 13 (1) : 74–77.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam

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