Tr-PEG5-OH

• UNSPSC Description:

  Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/tr-peg5-oh.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCCOCCOCCOCCOCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

• Molecular Weight:

  480.59

• References & Citations:

  [1]Branderhorst HM, et al. Strong inhibition of cholera toxin binding by galactose dendrimers. Chem Commun (Camb). 2007 Dec 21;(47):5043-5.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  141282-24-8