BO-0742

• Description :

  BO-0742, a derivative of AHMA and N-mustard, is a potent anti-cancer agent. BO-0742 significantly suppresses the growth of xenografts of human breast and ovarian cancers in mice[1].

• CAS Number :

  [774234-08-1]

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/bo-0742.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OCC1=CC(OCCN(CCCl)CCCl)=CC(NC2=C3C=CC=CC3=NC4=CC=CC=C42)=C1

• Molecular Formula :

  C26H27Cl2N3O2

• Molecular Weight :

  484.42

• References & Citations :

  [1]Chien-Hsin Lee, et al. BO-0742, a derivative of AHMA and N-mustard, has selective toxicity to drug sensitive and drug resistant leukemia cells and solid tumors. Cancer Lett. 2009 Apr 18;276 (2) :204-11.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported