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LB-205

CAT: 0804-HY-118352Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118352Size:1 Each
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Description
LB-205 is a pan-histone deacetylase inhibitor (HDACi) . LB-205 can be used for the research of acute traumatic brain injury[1][2].
CAS Number
1113025-86-7
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lb-205.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1S)NCCCCCC(NC2=CC=CC=C2)=O
Molecular Formula
C19H22N2O2S
Molecular Weight
342.46
References & Citations
[1]Lu J, et, al. Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury. Proc Natl Acad Sci U S A. 2013 Jun 25;110 (26) :10747-52. |[2]Lu J, et, al. Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease. Proc Natl Acad Sci U S A. 2011 Dec 27;108 (52) :21200-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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