TMC-205

• Description:

  TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter[1].

• UNSPSC:

  12352005

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tmc-205.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CNC2=C1C=CC(/C=C/C(C)=C)=C2)O

• Molecular Formula:

  C14H13NO2

• Molecular Weight:

  227.26

• References & Citations:

  [1]Gao Y, et al. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014;5 (8) :863-867. Published 2014 Jun 23.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Microbial Metabolite

• CAS Number:

  [403646-00-4]