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AC-93253

CAT: 0804-HY-118343Size: 10 mgDry Ice: NoHazardous: No
CAT#: HY-118343Size: 10 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AC-93253 is a selective, potent SIRT2 inhibitor. AC93253 can inhibit SIRT2 with an IC50 value of 6 μM. AC93253 can be used for the research of tumors[1].
CAS Number
[108527-83-9]
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-93253.html
Purity
99.3
Solubility
10 mM in DMSO
Smiles
CC1(C)C2=C(C=CC=C2)N(C)/C1=C/C=C/C3=[N+](CC)C4=C(C=CC=C4)S3.[I-]
Molecular Formula
C23H25IN2S
Molecular Weight
488.43
References & Citations
[1]Zhang, Yingjia et al. Identification of a small molecule SIRT2 inhibitor with selective tumor cytotoxicity. Biochemical and biophysical research communications vol. 386,4 (2009) : 729-33.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT1; SIRT2; SIRT3

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