AC-90179

• Description :

  AC-90179 is a selective 5-HT2A receptor inverse agonist (Ki = 2.1 nM) and 5-HT2C antagonist, a potential antipsychotic compound[1].

• CAS Number :

  [359878-19-6]

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ac-90179.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N(CC1=CC=C(C)C=C1)C2CCN(C)CC2)CC3=CC=C(OC)C=C3.Cl

• Molecular Formula :

  C23H31ClN2O2

• Molecular Weight :

  402.96

• References & Citations :

  [1]Kimberly E. Vanover, et al. Pharmacological Characterization of AC-90179 [2- (4-Methoxyphenyl) -N- (4-methyl-benzyl) -N- (1-methyl-piperidin-4-yl) -acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist. Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT2 Receptor