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BI 703704

CAT: 0804-HY-117962ASize: 1 EachDry Ice: NoHazardous: No
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Description
BI 703704 is a potent soluble guanylate cyclase (sGC) activator. BI 703704 inhibits the progression of diabetic nephropathy in the ZSF1 rat[1].
CAS Number
2740807-77-4
UNSPSC
12352005
Target
Guanylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bi-703704.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(C2=CSC(N3C[C@H](CC4)[C@@H](C(O)=O)[C@H]4C3)=N2)=C(OCC5=CC=C(C(N6CCCCC6)=O)C=C5C)C=C1
Molecular Formula
C32H37N3O4S
Molecular Weight
559.72
References & Citations
[1]Boustany-Kari CM, et al. A Soluble Guanylate Cyclase Activator Inhibits the Progression of Diabetic Nephropathy in the ZSF1 Rat. J Pharmacol Exp Ther. 2016 Mar;356 (3) :712-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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