Complex III-IN-1

• Description:

  Complex III-IN-1 (Compd 4c-2) is a complex III inhibitor. Complex III-IN-1 shows antifungal activity with an EC50 of 18.53 mg/L against sclerotinia sclerotiorum[1].

• UNSPSC:

  12352005

• Target:

  Fungal; Mitochondrial Metabolism

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/complex-iii-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S (C1=CC=C (Cl) S1) (NC/C=C (C) /CC/C=C (C) \C) =O

• Molecular Formula:

  C14H20ClNO2S2

• Molecular Weight:

  333.90

• References & Citations:

  [1]Song, X., et al. Synthesis, antifungal activity, and molecular dynamics study of novel geranyl aromatic sulfonamide compounds as potential complex III inhibitors. Med Chem Res 31, 628–642 (2022) .

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported