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Y13g

CAT: 0804-HY-115910Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115910Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Y13g is the potent inhibitor of both AChE and IL-6. Interleukin-6 (IL-6) and acetylcholinesterase (AChE) are two important targets implicated in progression of Alzheimer's Disease (AD). Y13g reverses the STZ -induced memory deficit, and shows histopathology similarly as in normal animals[1].
CAS Number
2766380-73-6
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/y13g.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(O)=C(C(OC)=C1)C(CCCN2CCNCC2)=O
Molecular Formula
C16H24N2O4
Molecular Weight
308.37
References & Citations
[1]Kaur S, et al. Design, molecular Docking, synthesis and evaluation of xanthoxylin hybrids as dual inhibitors of IL-6 and acetylcholinesterase for Alzheimer's disease. Bioorg Chem. 2022;121:105670.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; IL-6

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