RegisterLogin

Xanthosine

CAT: 0804-HY-W011527-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W011527-01Size:50 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Xanthosine is a nucleoside derived from xanthine and ribose. Xanthosine activates the AMPK/FoxO1/AKT/GSK3β signaling cascade. Xanthosine promotes cell proliferation and regulates blood glucose metabolism. Xanthosine increases milk production in cows and goats. Xanthosine is used in mammary stem cell and type 2 diabetes research[1][2][3][4][5][6].
CAS Number
[146-80-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/9-__2R,3R,4S,5R_-3,4-Dihydroxy-5-_hydroxymethyl_tetrahydrofuran-2-yl_-9H-purine-2,6-diol.html
Purity
99.99
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(NC3=O)=O)=C3N=C2)O1
Molecular Formula
C10H12N4O6
Molecular Weight
284.23
Precautions
H302, H315, H319
References & Citations
[1]Choudhary S, et, al. Examination of the xanthosine response on gene expression of mammary epithelial cells using RNA-seq technology. J Anim Sci Technol. 2018 Jul 13;60:18.|[2]Choudhary RK, et al. In vitro expansion of the mammary stem/progenitor cell population by xanthosine treatment. BMC Cell Biol. 2012 Jun 14;13:14.|[3]Rauner G, et al. Xanthosine administration does not affect the proportion of epithelial stem cells in bovine mammary tissue, but has a latent negative effect on cell proliferation. Exp Cell Res. 2014 Oct 15;328 (1) :186-196.|[4]Ahmed SA, et al. Xanthosine, a purine glycoside mediates hepatic glucose homeostasis through inhibition of gluconeogenesis and activation of glycogenesis via regulating the AMPK/ FoxO1/AKT/GSK3β signaling cascade. Chem Biol Interact. 2023 Feb 1;371:110347. |[5]MOULTON, et al. Histamine release and pain production by xanthosine and related compounds. Br J Pharmacol Chemother. 1957 Sep;12 (3) :365-70.|[6]Capuco AV, et al. In vivo expansion of the mammary stem/ progenitor cell population by xanthosine infusion. Exp Biol Med (Maywood) . 2009 Apr;234 (4) :475-82.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite

Related Products

CatalogName
HY-107231-01Xanthiside
HY-117732Xanthorin
HY-N0126-01Xanthone
HY-W017389-01Xanthine
HY-N10985Xanthone V1a
HY-N2964BR-xanthone A
HY-N0126R-01Xanthone (Standard)
HY-W017389R-01Xanthine (Standard)
HY-W017389S1-01Xanthine-15N2
HY-151974-01Xanthine oxidoreductase-IN-4

Alternative Products

CatalogName
296561-01Xanthosine
M19863-01Xanthosine dihydrate
B7976-.01Xanthosine-TP
TRC-X742102-1MGXanthosine-13C5
372077Xanthosine discontinued
RM-X140941-01Xanthosine 5′-diphosphate
T201502-01Xanthosine-5'-monophosphate

Popular Products