MPC-0767

CAT: 0804-HY-115499Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-115499Size:1 Each
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Description
MPC-0767 is a potent, selective, and orally active hsp90 inhibitor. MPC-0767 is an L-alanine ester proagent of MPC-3100 with improved chemical stability[1].
CAS Number
[1310540-32-9]
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mpc-0767.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](C)C(O[C@@H](C)C(N1CCC(CCN2C(SC3=C(Br)C=C(OCO4)C4=C3)=NC5=C(N)N=CN=C25)CC1)=O)=O.CS(=O)(O)=O.[H]O[H]
Molecular Formula
C26H36BrN7O9S2
Molecular Weight
734.64
References & Citations
[1]Se-Ho Kim, et al. Discovery of an L-alanine ester prodrug of the Hsp90 inhibitor, MPC-3100. Bioorg Med Chem Lett. 2015 Nov 15;25 (22) :5254-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP90

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