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TIQ-15

CAT: 0804-HY-115493Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115493Size:1 Each
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Description
TIQ-15 is a potent CXCR4 antagonist with an IC50 value of 6 nM for CXCR4 Ca2+ flux. TIQ-15 inhibits CYP450 2D6 with an IC50 value of 0.32 μM[1].
CAS Number
1380336-17-3
UNSPSC
12352005
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tiq-15.html
Solubility
10 mM in DMSO
Smiles
NCCCCN(C[C@@H]1NCC2=C(C=CC=C2)C1)[C@H]3CCCC4=C3N=CC=C4
Molecular Formula
C23H32N4
Molecular Weight
364.53
References & Citations
[1]Tahirovic YA, et, al. Discovery of N-Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties. ACS Med Chem Lett. 2018 Apr 9;9 (5) :446-451.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CXCR4

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