TIQ-A

• UNSPSC Description:

  TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent[1].

• Target Antigen:

  PARP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Field of Research:

  Cancer; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/tiq-a.html

• Purity:

  99.65

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C1NC2=C(C3=C1C=CC=C3)C=CS2

• Molecular Weight:

  201.25

• References & Citations:

  [1]Maksimainen MM, et al. Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs. Bioorg Med Chem. 2021 Dec 15;52:116511.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  420849-22-5