AT-1002

• Description:

  AT-1002, a 6-mer synthetic peptide[1], is a tight junction regulator and absorption enhancer[2].

• UNSPSC:

  12352005

• Target:

  Gap Junction Protein

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/AT-1002.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CS)C(N[C@@H]([C@H](CC)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C32H53N9O7S

• Molecular Weight:

  707.88

• References & Citations:

  [1]Li M, et al. Structure-activity relationship studies of permeability modulating peptide AT-1002. Bioorg Med Chem Lett. 2008 Aug 15;18 (16) :4584-6.|[2]Gopalakrishnan S, et al. Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer. Int J Pharm. 2009 Jan 5;365 (1-2) :121-30.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [835872-35-0]