Products for Research Use Only
RegisterLogin

Leukotriene B4

CAT: 0804-HY-107608Size: 25 μg (297.2 μM x 250 μL in Ethanol)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107608Size:25 μg (297.2 μM x 250 μL in Ethanol)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3].
CAS Number
71160-24-2
Product Name Alternative
LTB4; 5 (S),12 (R) -DiHETE
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Endogenous Metabolite; Leukotriene Receptor; PROTAC Linkers
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5,12-DiHETE.html
Concentration
297.2 μM * 250 μL in Ethanol
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O
Molecular Formula
C20H32O4
Molecular Weight
336.47
Precautions
H225, H319
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562|[2]S.WCrooks, et al. Leukotriene B4. The International Journal of Biochemistry & Cell Biology Volume 30, Issue 2, 27 March 1998, Pages 173-178.|[3]Takehiko Yokomizo, et al. Leukotriene B4: Metabolism and Signal Transduction. Archives of Biochemistry and Biophysics Volume 385, Issue 2, 15 January 2001, Pages 231-241.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
Phase 2
Isoform
Alkyl-Chain Linkers; Human Endogenous Metabolite

Related Products

CatalogName
HY-N12329-01Fumonisin B4
HY-P991231DI-B4
HY-N13983Arylomycin B4
HY-P5585Dermaseptin-B4
HY-N15393Cerexin B4
HY-N14299Fluvirucin B4
HY-N4218-01Saikosaponin B4
HY-116953Lipoxin B4
HY-N10469-01Bleomycin B4
HY-N12740Napyradiomycin B4

Alternative Products

CatalogName
YCA83678Leukotriene d4
453668-01Leukotriene F4
453661-01Leukotriene B5
MBS565375-01Leukotriene B4
MBS565414-01Leukotriene C4
sc-201050ALeukotriene E4
MBS5798472Leukotriene B3
453662-01Leukotriene C3

Popular Products