Uridine 5'-diphosphate-13C9 (dilithium)

Uridine 5'-diphosphate-13C9 (dilithium)

• UNSPSC Description: Uridine 5'-diphosphate-13C9 dilithium is 13C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor.
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds; P2Y Receptor
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease;Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/uridine-5-diphosphate-13c9-dilithium.html
• Solubility: 10 mM in DMSO
• Smiles: O=[13C](N1)N([13C@@H]2O[13C@H]([13CH2]OP(OP(O[Li])(O[Li])=O)(O)=O)[13C@@H](O)[13C@H]2O)[13CH]=[13CH][13C]1=O
• Molecular Weight: 424.96
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Ashleigh S Paparella, et al. Clostridioides difficile TcdB Toxin Glucosylates Rho GTPase by an SNi Mechanism and Ion Pair Transition State. ACS Chem Biol. 2022 Sep 16;17(9):2507-2518.|[3]Besada P, et al. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J Med Chem. 2006 Sep 7;49(18):5532-43.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported