7ß-Hydroxycholesterol-d7

CAT: 0804-HY-113341SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-113341SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7ß-Hydroxycholesterol-d7 is the deuterium labeled 7α-Hydroxycholesterol. 7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol can induce cellular oxidative stress, apoptosis, and necrosis, resulting in cytotoxicity. 7β-hydroxycholesterol has antitumor activity[1][2].
CAS Number
[349553-97-5]
UNSPSC
12352211
Target
Apoptosis; Interleukin Related; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Immunology/Inflammation; Others
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Purity
97.0
Solubility
DMF : ≥ 2mg/mL|DMSO : ≥ 0.1mg/mL|Ethanol : ≥ 20mg/mL
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=C[C@@H]3O)C
Molecular Formula
C27H39D7O2
Molecular Weight
409.70
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Anne Vejux, et al. 7-Ketocholesterol and 7β-hydroxycholesterol: In vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity. Biochem Pharmacol. 2020 Mar;173:113648.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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