DMHAPC-Chol

• Description:

  DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA[1].

• UNSPSC:

  12352200

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Liposome

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dmhapc-chol.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@H]([C@]1(CC[C@]2([C@@]3(CC=C4C[C@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)OC(NCCC[N+](C)(CCO)C)=O)[H])[H])[H])CCCC(C)C.[I-]

• Molecular Formula:

  C35H63IN2O3

• Molecular Weight:

  686.79

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]A Percot. et al. A hydroxyethylated cholesterol-based cationic lipid for DNA delivery: effect of conditioning. Int J Pharm. 2004 Jun 18;278 (1) :143-63.|[2]Dominique Briane, et al. Inhibition of VEGF expression in A431 and MDA-MB-231 tumour cells by cationic lipid-mediated siRNA delivery. J Drug Target. 2012 May;20 (4) :347-54.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [774598-29-7]