(1R,2S)-NCD38 (TFA)

(1R,2S)-NCD38 (TFA)

• CAS Number: 2078047-42-2
• UNSPSC Description: (1R,2S)-NCD38 TFA is an enantiomer of NCD38 TFA. NCD38 TFA is a LSD1-selective inhibitor[1][2].
• Target Antigen: Histone Demethylase
• Type: Reference compound
• Related Pathways: Epigenetics
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/1r-2s-ncd38-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C(NCC3=CC=CC(Cl)=C3)=O)CCCCN[C@H]4[C@H](C5=CC=CC=C5)C4.O=C(O)C(F)(F)F
• Molecular Weight: 680.16
• References & Citations: [1]G R Sareddy, et al. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017 Apr 27;36(17):2423-2434.|[2]Yosuke Ota , et al. Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors. Bioorg Med Chem. 2018 Feb 1;26(3):775-785.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported