AGI-25696

• Description:

  AGI-25696 is a methionine adenosyltransferase 2A (MATA2) inhibitors useful for treatment of cancer. AGI-25696 blocks growth of MTAP-deleted tumors in vivo.

• UNSPSC:

  12352005

• Target:

  Methionine Adenosyltransferase (MAT)

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/AGI-25696.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C (C2=CC=C3N=CC=CC3=C2) =CNC4=C (C5=CC=CC=C5) C (C6=CC=CC=C6) =NN14

• Molecular Formula:

  C27H18N4O

• Molecular Weight:

  414.46

• References & Citations:

  [1]Agios. Targeting MAT2A in MTAP-deleted Cancers. Presented at the American Association for Cancer Research (AACR) Annual Meeting, April 14-18, 2018, Chicago, IL, USA

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2201066-35-3