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VH032-thiol-C6-NH2

CAT: 0804-HY-111824Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111824Size:1 Each
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Description
VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.
CAS Number
2098836-63-4
Product Name Alternative
VHL Ligand-Linker Conjugates 14; E3 ligase Ligand-Linker Conjugates 29
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-binding-moiety-4.html
Solubility
10 mM in DMSO
Smiles
CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(SCCCCCCN)(C)C)NC(C)=O)=O)=O)C=C2
Molecular Formula
C29H43N5O4S2
Molecular Weight
589.81
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13 (5) :514-521.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)

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Alternative Products

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MBS3844299-01VH032-thiol-C6-NH2
A19847-10VH032-thiol-C6-NH2 10mg
A19847-5VH032-thiol-C6-NH2 5mg
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A19857-10VH032 thiol 10mg
A19857-100VH032 thiol 100mg
A19857-5VH032 thiol 5mg
A19857-50VH032 thiol 50mg
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